C23H24FN6O9P.2Na

It is a precursor drug of active metabolite R406 and a Syk inhibitor.

C25H24N6O2

Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL).

C26H23N7O2

Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor.

C23H30N8O

Ribociclib (lee011) is a highly specific CDK4 and Cdk6 inhibitor with oral activity

C21H15ClF4N4O3

Regorafenib is a new oral small molecule multi-kinases inhibitor. It can inhibit the target kinases associated with angiogenesis and tumorigenesis.

C16H20N6O

a JAK3-selective inhibitor for the treatment of rheumatoid arthritis

C21H23N7O2S

Pazopanib is a novel oral vascular generation inhibitor which may interfere stubborn tumor survival and new blood vessels generation growth needed

C22H18N4OS

Axitinib is a small molecule tyrosine kinase inhibitor, effective against multiple targets, including VEGF receptors 1, 2 and 3.

C29H26ClFN4O4S

Lapatinib is a tyrosine kinase inhibitor which can effectively inhibit the tyrosine kinase activity of human epidermal growth factor receptors 1 and 2 (ErbB1, ErbB2).

C22H27FN4O2

A multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic.

C21H22Cl2FN5O

Crizotinib is a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.

C30H34N4O2

Alectinib (CH5424802) is an efficient ALK inhibitor.

C21H16ClF3N4O3

Sorafenib is an oral receptor tyrosine kinase inhibitor that inhibits Raf serine/threonine kinases and receptor tyrosine kinases (vascular endothelial growth factor receptors 1, 2, 3 and platelet-derived growth factor-b, Flt-3 and c-kit) that are implicated in tumorigenesis and tumor progression.

C22H26ClN7O2S

Dasatinib is an oral potent oncogenic kinase inhibitor, which can block signal of cancer cell replication acceleration.

C22H23N3O4.HCl

Erlotinib hydrochlorate is a small molecule tyrosine kinase inhibitor